Dr Hannah Smith

BSc, MRes, PhD

School of Medicine and Population Health

Research Associate

Hannah Smith
Profile picture of Hannah Smith
hannah.l.smith@sheffield.ac.uk
The Medical School

Full contact details

Dr Hannah Smith
School of Medicine and Population Health
The Medical School
Beech Hill Road
Sheffield
S10 2RX
Profile

Hannah joined the University of Sheffield in 2024 as a Research Associate in the Cancer and Bone (CAB) Lab, under Dr Alanna (Leni) Green). Hannah is investigating the impact of the bone microenvironment on multiple myeloma dormancy, with a focus on bone cell and cancer interactions.

Hannah completed her PhD at the University of Southampton in 2022, ‘Developing a 3D Multicellular Bone Model of Osteosarcoma’. Following completion she stayed at the University of Southampton as a research associate investigating the suppressive mechanisms of macrophages in a cancer setting.

Qualifications

PhD in Cancer Sciences, University of Southampton, 

MRes in Translational Cancer Medicine, King’s College London

BSc in Biological Sciences, University of Essex

Research interests

My research interests focus on bone/immune/cancer interactions. I am interested in how bone cell signaling regulates tumourigenic development in cancer, both primary and metastatic. I am also interested in how immune regulation is disrupted in the tumour microenvironment. 

Publications

Journal articles

  • Smith HL, Foxall RB, Duriez PJ, Teal EL, Hoppe AD, Kanczler JM, Gray JC & Beers SA (2025) . The Journal of Immunology, 214(4), 714-725.
  • Smith HL, Beers SA, Kanczler JM & Gray JC (2024) . The FASEB Journal, 38(24).
  • Griffiths J, Hussain K, Smith HL, Sanders T, Cox KL, Semmrich M, MÃ¥rtensson L, Kim J, Inzhelevskaya T, Penfold CA , Tutt AL et al (2020) . Journal for ImmunoTherapy of Cancer, 8(2), e001557-e001557.
  • Eisenblaetter M, Flores-Borja F, Lee JJ, Wefers C, Smith H, Hueting R, Cooper MS, Blower PJ, Patel D, Rodriguez-Justo M , Milewicz H et al (2017) . Theranostics, 7(9), 2392-2401.
  • Smith HL, Gray JC, Beers SA & Kanczler JM () . International Journal of Molecular Sciences, 24(4), 3667-3667.
  • Smith HL, Beers SA, Gray JC & Kanczler JM () . International Journal of Molecular Sciences, 21(15), 5499-5499.