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Downloads

TSD 8

TSD 8:

TSD 9

TSD 9:

Related publication

D Papaioannou, J Brazier, S Paisley (2013) . Value in Health, 16 (4), pp. 686-695.

TSD 10 [updated and replaced by TSD22]

TSD 10:

Related publication

L Longworth, D Rowen (2013) . Value in Health, 16(1), pp. 202-210.

TSD 11

TSD 11:

TSD 12

TSD 12:

EQ-5D matrix (Excel, 13KB)

Related publication

R Ara, A Wailoo (2012) . Value in Health, 15(6)

TSD 22 

TSD 22: (Updated Sept 2026) 

TSD22: One page summary

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The intention behind the TSDs is not to be prescriptive, but rather to explain the requirements for measuring and valuing health set out in the , and to provide guidance on methods that meet these requirements.

TSD 8 provides an introduction to the NICE reference case, including the preference for using the EQ-5D, and an overview of what to do when EQ-5D is not available, what to do when EQ-5D is not appropriate and how to determine whether or not the EQ-5D is appropriate for any given condition and intervention outcome.

The remaining four TSDs provide further information on these issues arising from the reference case, including the use of literature reviews to obtain suitable health state utility values, the use of mapping when EQ-5D values are not available, the use of alternative measures when the EQ-5D is not appropriate and the special issues that arise from using health state utility values in decision models.

Instructions for citing these documents can be found on page 3 of each TSD.