Dr
Xinyue
Chen

School of Chemical, Materials and Biological Engineering

Experimental Officer (Nanocharacterisation)

Xinyue Chen
Profile picture of Xinyue Chen
xinyue.chen@sheffield.ac.uk
+44 114 222 5476
Royce Discovery Centre

Full contact details

Dr Xinyue Chen
School of Chemical, Materials and Biological Engineering

Royce Discovery Centre
5 Portobello Street

Sheffield

S1 4ND

Profile

Xinyue has an interdisciplinary educational background (BSc in theoretical physics, MRes in biochemistry and PhD in biophysics) and extensive research experience in both biophysics and materials science.

Xinyue started embracing atomic force microscopy (AFM) during her PhD in 2012, and it’s been a big part of her work ever since. 

After moving to Sheffield in 2016 to join the world leading SPM group as a PDRA, Xinyue has worked daily with AFM, and over the years, has applied it to over 30 independent research projects; spanning from single molecules and supramolecular assemblies to intact tissues, and from semiconductors to metal alloys. 

As Technical Specialist, Xinyue manages the Nanocharacterisation Facility, supporting a large AFM fleet, as well as nanoindenters and an optical profiler. She is actively engaged in her own research in metrology whilst also supporting the research of others through advice, collaboration, experimental work, and training.

Publications

Journal articles

  • Beer C, Bahri M, Baldinozzi G, Ishimaru M, Zhang Y, Sharpe MK, McAleese CD, Chen X, Bohns F, Manning T , Browning ND et al (2025) . Acta Materialia, 298, 121391-121391.
  • Wu B, Zhang G, Ji J, Luo R, Chen J, Liu F, Coy E, Moya SE, Li Q, Suo X , Chen X et al (2024) . Advanced Functional Materials, 34(14).
  • Ngalim SH, Yusoff N, Johnson RR, Abdul Razak SR, Chen X, Hobbs JK & Lee YY (2022) . Progress in Biophysics and Molecular Biology, 175, 63-72.
  • Wacnik K, Rao VA, Chen X, Lafage L, Pazos M, Booth S, Vollmer W, Hobbs JK, Lewis RJ & Foster SJ (2022) . mBio, 13(4).
  • Chen X, Hughes R, Mullin N, Hawkins RJ, Holen I, Brown NJ & Hobbs JK (2021) . Nanoscale, 13(43), 18237-18246.
  • Hughes R, Chen X, Cowley N, Ottewell PD, Hawkins RJ, Hunter KD, Hobbs JK, Brown NJ & Holen I (2021) . Cancers, 13(6).
  • Chen X, Hughes R, Mullin N, Hawkins RJ, Holen I, Brown NJ & Hobbs JK (2020) . Biophysical Journal, 119(3), 502-513.
  • Hughes R, Chen X, Hunter KD, Hobbs JK, Holen I & Brown NJ (2019) . The FASEB Journal, 33(11), 12768-12779.
  • Chen X & Richter RP (2019) . Interface Focus, 9(2).
  • Chen X, Bonfiglio R, Banerji S, Jackson DG, Salustri A & Richter RP (2016) . Biophysical Journal, 110(12), 2779-2789.
  • Chen X, Qoutah WW, Free P, Hobley J, Fernig DG & Paramelle D (2012) . Australian Journal of Chemistry, 65(3), 266-266.
  • Chen X, Swift HC, Hole P, Humphris ADL & Hobbs JK () . Nanoscale.

Conference proceedings

  • Chen X, Hughes R, Mullin N, Hawkins R, Holen I, Brown N & Hobbs J (2019) Supracellular Mechanical Architecture of the Intact Bone Microenvironment. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, Vol. 48 (pp S100-S100)
  • Hughes R, Allocca G, Holen I, Chen X, Hobbs J & Brown N (2017) Breast Cancer Metastasis To Bone: The Perivascular Niche. JOURNAL OF VASCULAR RESEARCH, Vol. 54 (pp 55-56)

Datasets

  • Wacnik K, Rao V, Chen X, Lafage L, Pazos M, Booth S, Vollmer W, Hobbs J, Lewis R & Foster S .
  • Wacnik K, Rao V, Chen X, Lafage L, Pazos M, Vollmer W, Hobbs J, Lewis R & Foster S .

Other

  • Pyne A, Shephard N, Gamill M, Whittle S, Du M, Beton J, Catley T, Chen X, Firth T, Holmes E , Moorehead R et al () .